The film follows Sab, a transporter for local drug cartels. Amidst an imminent war between her superiors, Sab also deals with her dying grandmother's last wish that she bear a child. When Sab learns that she's barren, this leads her to darker practices and revelations. MARKADO: Bakunawa sa Duha Ka-Manglahing Takna is the first ever full-length film to be completely made and produced by local filmmakers from Cagayan de Oro city.