Continents apart from one another, two farming families aim to reinvent themselves on their land. One family—a strong-willed French matriarch and the son she raised among her vines—tends a centuries-old, biodynamic vineyard in the Southern Rhône. Across the ocean in Humboldt, California, another family—a brash father and his more reserved son—carefully manage a state-recognized, organic cannabis farm. The feature documentary WEED & WINE interweaves their stories, urging comparisons and teasing out contradictions between France’s revered winemaking traditions and the artisan culture emerging alongside the legal cannabis industry.