Four friends living in Rome: Alberto, a lawyer who is desperately trying to have a baby with her wife using "targeted sexual encounters"; Christian, a young and handsome footballer in a major team; Sandro, a gas technician with a passion for ladies; Andrea, a dentist. When Andrea's wife leaves him to spend time on her book and Sandro is forced out of his house by his own spouse, they both ends up at Christian's flat to taste a new life as singles.