A Safe House is about a young man named Bill Solino who discovers not only that his deceased father was a mobster but also that his uncle, who raised him, may have had a hand in his fathers murder twenty years earlier. When Bill gets into some trouble, he finds himself on the run from the law hiding out a safe house and in a moral crisis, wherein he feels that that allowing his uncle to get him off the hook would make him complicit in his dad's death.