This offbeat dark comedy take place when four friends (Brisco, J Rob, Pedro, and Hay Love) have a backyard bar-b-q and decide to come up on some bud. Not knowing where to turn, because the streets have been dry for a few months, they end up scoring from the son of a over protective mob figure by the name of Fredrico, who vows, if anything should happen to his son, their will be hell to pay. After a tragic accident, the four friends are on the run with only one person to turn to, Krego, Brisco`s long time friend. Krego confirms to them, Fredrico is a very powerful man, and there is no escaping his fury. Their only option is to change their appearance through underground plastic surgery, which would take them on a five hundred mile road trip. Along the way, they will have to avoid Fredrico`s beautiful assassin, Venus, and other unsavory characters, leaving them to ponder the question, was it just dumb luck, or was it the bud?