Panimalai is an imaginary hill station, where there is a news anchor (Balaji Mohan), whose only aim is get TRP's for his channel. Meanwhile a salesman Aravind (Dulquer Salmaan), an orphan and happy-go-lucky good talker meets Dr. Anjana (Nazriya), a confused, soft spoken girl who is unable to express her feelings properly and has a dominating fiancée who is a control freak. There are also other characters like Health Minister Sundaralingam (Pandiarajan), Superstar Boomesh (John Vijay), Kudikara Sangam Thalaivar Ravi (Robo Shankar), a feudal landlord (Vinu Chakravarthi) and Anjana's step mother (Madhoo). One day, people in the scenic hill station get affected by 'dumb flu' and lose their voice. Finally, state government issues an order banning people from talking to avoid spreading of this contagious disease.