Attempting to save their group's singing career, Reggie Mendoza (Regine Velasquez), a self-confessed grandma's girl, and Mikki Tolentino (Mikee Cojuangco), a misandrist tomboy and a toast of her family, discover Donnette Legaspi (Donna Cruz), a vainglorious spoiled brat coming from a rich family, while singing in a restroom, to be part of their musical trio, DoReMi. Despite their drastic differences in both their personalities, lifestyle and principles, their shared love for music allowed them to consider pursuing a music career in Japan only to find out at the immigration office of a local airport that a fly-by-night placement or recruitment agency had falsified their documents and faked their passports. Due to this mishap and fear of humiliation and concern of their families, the girls travel to a laid back province, putting themselves in a self-imposed exile after the embarrassment they faced after chasing their dreams.