The story continues in Return of the Cartoon Man. For about six months, Roy and Karen have been comfortably living their lives as human cartoons. One day, they are visited by a mysterious salesman named Peter who attempts to question them about their bizarre transformation for unspecified reasons. Meanwhile, Simon succeeds in opening a portal from the Second Dimension back into the real world, and begins terrorizing innocent bystanders. Valerie finds her way through the portal as well, determined to find her way back to Roy. Before long, all of the threads come together, the investigation into Oswald Sherzikien's whereabouts is re-opened, and it becomes clear that the whole situation is bigger in scope than anyone ever imagined.