Brother Frank is about the searching experiments of a young artist, Odessa, as she is confronted with a story that is bigger and more meaningful than anything in the history of her work. After floating through the carefree art scene she's immersed in, she follows an intuition to pursue a compelling anecdote. She is plopped into a more realistic world where distressing events and painful awkwardness intermingle with recurring imagery and beautiful scenery that she is too shy to capture on film. We follow Odessa on her journey to meet Brother Frank, an elderly monk ostracized by his church, accompanied by her overwhelming trepidation that causes his poignant tale to slip out of her grasp.